Our vision is to be the accepted PAIONeer in sedation and anesthesia; helping advance patient care.
Procedural sedation is a technique of administering sedatives or dissociative agents, with or without analgesics, to induce a state that allows the patient to tolerate unpleasant procedures such as colonoscopy while maintaining cardiorespiratory function.
General anesthesia leads to loss of consciousness and loss of sensation of patients through the administration of anesthetics in combination with opioid analgesics. This enables medical procedures such as major surgery, that would otherwise be unbearable, to be carried out with minimal discomfort or added risk.
The number of surgical procedures worldwide continues to grow driven by population growth and other factors such as obesity, low physical activity levels, dietary habits, smoking, and alcohol. Current estimates place the number of surgical procedures annually at greater than 230 million1; the majority in the areas of general, orthopaedic/trauma and obstetric/gynaecological surgery.
The market for sedation and anesthesia has been short on pharmaceutical development during the last decade and there remains room for innovation. Sedative and anesthetic safety is continuously reviewed as part of quality assessments and includes such elements as efficacy, unintended intra-operational awareness, respiratory depression, hemodynamic stability, post-operative/procedure emergence and recovery, long term effects of anesthesia and patient morbidity.
1 The Lancet: Estimate of the global volume of surgery in 2012: an assessment supporting improved health outcomes